DEFINE-FLAIR & IFR-SWEDEHEART Outcome Data Release International Meeting

A dedicated international meeting discussing the DEFINE FLAIR clinical trial results whilst showing practical use of state-of-art iFR and FFR technology.

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During the recent Scientific Sessions of the American College of Cardiology (ACC 2017) the results of two large studies in coronary physiology, DEFINE FLAIR and iFR SWEDEHEART, were presented.

Together, the population of these two studies exceed that of all available trials on FFR. The conclusions are highly relevant to understand the present and future of physiological guidance of coronary revascularisation.

We would like to share with you, within one week of its official presentation at ACC 2017, the results of these two trials at a dedicated international meeting to be held at Hospital Clinico San Carlos, Madrid, which will also include live case transmissions from the same Hospital showing practical use of state-of-art iFR and FFR technology.


Dr Rasha Al-Lamee

Dr. Justin Davies is a leading clinical academic in the field of interventional cardiology.  Based as a consultant interventional cardiologist at Hammersmith Hospital, part of Imperial College Healthcare NHS Trust London, he has pioneered the development of several new clinical techniques from bench top to the clinical catheter laboratory.  Most recently these technological breakthroughs include iFR (instant wave-free ratio) and iFR SCOUT both of which make use of a better understanding of coronary haemodynamics.  Together with improved sensor and microprocessor technology, iFR allow for the first time the evaluation of the severity of a coronary stenosis without the need for administration of powerful vasodilator drugs.

Although currently a practicing interventional consultant cardiologist, Justin’s science training was a doctorate in fluid dynamics and computational programming.  This led to the development of analysis techniques such as coronary wave intensity analysis and the wave-reservoir theory both of which are increasingly used in research studies.  In his post-doctoral days he has continued to work on the development of mathematical algorithms to aid understanding of large artery physiology and to develop new tools to assess arterial disease.

The holder of 15 patents, he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards.  He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, and ORBITA studies.

Justin has an interest in renal denervation, and has lead first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies) and hypertension.

Dr Rasha Al-Lamee

Prof. Javier Escaned  is Consultant Interventional Cardiologist / Associate Professor and Head of Section, Cardiology Department, Hospital Clinico San Carlos (Madrid, Spain). 

He trained as a cardiologist the United Kingdom (Queen Elizabeth University Hospital, Birmingham and Walsgrave Hospital, Coventry) before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. 

Author of more than 200 scientific articles, books and book chapters on different aspects of interventional cardiology, imaging and physiology, his latest contribution is the textbook “Coronary Stenosis. Imaging, Structure and Physiology”, co-edited with Patrick W Serruys. He is currently co-director of EuroPCR. Some of his additional interests are philosophy, education and music.

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Target Audience

  • Interventional cardiologists
  • Interventional cardiology fellows

This live stream was sponsored by Philips Volcano.

Learning Objectives

This live streamed meeting is intended to inform and educate cardiologists on:

  • The DEFINE FLAIR and iFR SWEDEHEART clinical trial design and outcomes
  • To assess how these trial results may influence the use and adoption of coronary physiological assessment
  • How expert operators integrate coronary physiology in their daily practice

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