Simple Education Interventional Cardiology: Coronary Physiology Course (iFR, FFR, CFR, CT-FFR), June 2018, London

2 day course, June 11-12th 2018 London, W2 2EA

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Simple Education essential guides Advances in Coronary Physiology is the premier international course in coronary physiology. This is the 6th year this 5* rated course has been run which has quickly become established as the premier global interventional course in state-of-the-art coronary physiology. The course provides all you need to know to understand coronary physiology from learning the background basics of coronary physiology to understanding the clinical trial data and implementation of coronary physiology in the catheter laboratory. 

An online teaching resource, the Simple Education application, will give you access to video content from the days' talks, and a raft of other online educational and learning resources which continue your learning experience and  connect you with the interventional community after the course finishes.



Dr Justin Davies

Dr Justin Davies is a consultant 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial 
College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
 work on the development of mathematical algorithms to aid 
understanding of large artery physiology and to develop new
 tools to assess arterial disease. The holder of several patents,
 he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies). 

Dr Javier EscanedProf Javier Escaned is Consultant Interventional Cardiologist / Associate Professor and Head of Section, Cardiology Department, Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom (Queen Elizabeth University Hospital, Birmingham and Walsgrave Hospital, Coventry) before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. Author of more than 200 scientific articles, books and book chapters on different aspects of interventional cardiology, imaging and physiology, his latest contribution is the textbook “Coronary Stenosis. Imaging, Structure and Physiology”, co-edited with Patrick W Serruys. He is currently co-director or EuroPCR. Some of his additional interests are philosophy, education and music.

Dr Sayan SenDr Sayan Sen is a Consultant Interventional Cardiologist and
NIHR Clinical Lecturer at Imperial College London. His research
interests are dedicated to improving patient care. As such, they
include the development and validation of new diagnostic tools,
determining how the design of comparative efficacy studies can
affect clinical use of competing therapies and the development
and application of tools that permit a more patient centered
approach to therapy. He studied Medicine at University College London (UCL), achieving a First Class (Honours) Bachelor of Science degree in Medical Sciences & Neuroscience in 2000 and graduated with distinction (Surgery) in his final MBBS Examinations in 2003. He trained as a junior doctor on the Hammersmith and UCL medical rotations prior to being appointed as a Cardiology Specialist Registrar in the North West London region in April 2006 and a NIHR clinical Lecturer in 2013. One of the themes of his research is to determine the need for potent vasodilators when assessing coronary stenosis severity. Working with Dr Justin Davies, Dr Sen’s PhD introduced and developed a new technique of stenosis evaluation (the instantaneous wave-free ratio, iFR). In addition to being the Principal Investigator of several first in man physiological studies, he was also the Medical Director of the DEFINE FLAIR trial – a global multi-centre randomized study that has recently demonstrated the non-inferiority of iFR to FFR for revascularisation decision-making in over 2500 patients. 

Dr Rasha Al-Lamee

Dr Rasha Al-Lamee is an Interventional Cardiologist at Imperial College Healthcare NHS Trust in London, UK. Dr Al-Lamee’s research interests are complex coronary intervention, coronary physiology and invasive intravascular assessment. She is currently leading the ORBITA trial as part of a PhD programme under the supervision of Dr Justin Davies and Professor Darrel Francis. At Imperial College she is actively involved in the development and recruitment for a number of multi-centre clinical trials. Dr Al-Lamee has over 30 peer-reviewed publications and has presented at international Cardiology conferences worldwide throughout her clinical career. She studied at the University of Oxford and University College London. She went onto complete her training as a junior doctor on the Barts and the London Medical rotation before being appointed as a Specialist Registrar on the North West London Cardiology rotation in 2006. Dr Al-Lamee has eleven years of Cardiology experience and completed three years of Interventional Fellowship training at Hammersmith Hospital in London. She also spent one year training as an Interventional Fellow under the supervision of Professor Antonio Colombo in Milan. She completed specialist training in Cardiology in 2013.

Dr Christopher Cook

Dr Christopher Cook is a Medical Research Council Clinical
Fellow at Imperial College London, undertaking a PhD in
coronary physiology under the supervision of Dr Justin Davies.
He studied Medicine at University College London (UCL) and
graduated with Distinction (Clinical Medicine and Clinical
Sciences) in his final MBBS Examinations in 2009. He achieved
a First Class (Honours) Bachelor of Science degree in
Physiology undertaking a period of research at The Hatter
Cardiovascular Institute. He was awarded ‘The Dean’s List’ for outstanding performance in the Faculty of Life Sciences. In total he was awarded 17 prizes including the prestigious Gold Medal Medicine (proxime accessit). In 2014, he was awarded the Imperial Valve and Cardiovascular Course Young Investigator Prize. In 2015 he was awarded the inaugural EuroPCR’s Got Talent Award. In 2017 he was elected onto the EuroPCR Clinical Programme Committee.

Dr John Davies

Dr Allen Jeremias is the Director of Interventional Cardiology
Research and Associate Director of the Cardiac Catheterization
Laboratory at St. Francis Hospital, Roslyn, NY. He was
previously an Associate Professor and the Director of the
Cardiac Catheterization Laboratory at Stony Brook University
Medical Center. He is also a member of the Cardiovascular
Research Foundation, New York, where he currently serves as
the Director of the Physiology Core Laboratory. Dr Jeremias
earned his medical degree at Heinrich-Heine-University School of Medicine in Düsseldorf, Germany, and a Master of Science degree at Harvard Medical School. He completed his Medical training at The Cleveland Clinic Foundation, Stanford University School of Medicine, as well as Beth Israel Deaconess Medical Center, Harvard Medical School.

Dr Jeremias is board certified in cardiovascular medicine and interventional cardiology and is a Fellow of the American College of Cardiology as well as the Society for Cardiovascular Angiography and Interventions. Dr Jeremias has numerous publications in the area of interventional cardiology and is the editor of the Medical Text Cardiac Intensive Care. He is the author of Your Personal Guide to Angioplasty, a patient-centered book focusing on coronary artery disease and various treatment options. He also is the recipient of numerous awards, including Castle Connolly’s Top Doctors: New York Metro Area, 2009 – 2016.

Professor Carlo Do Mario

Dr Yousif Ahmad is a Clinical Research Fellow and Specialist Registrar in Interventional Cardiology at Imperial College London. After graduating with Honours and multiple distinctions from the University of Nottingham he combined his clinical training with research under the supervision of Professor Gregory Lip. He completed his Membership of the Royal College of Physicians and authored several publications on atrial fibrillation which have been cited by international guidelines.

He was subsequently appointed to the competitive and prestigious Academic Clinical Fellowship in Cardiology at Imperial College London in 2013 and completed an Interventional Fellowship in 2015. He is currently a Clinical Research Fellow with his research interests spanning all of adult interventional cardiology, with particular emphasis on coronary physiology and the improvement of patient outcomes through tailored therapy.

Dr Nicolas Foin

Prof Amir Lerman, is a professor of medicine and a consultant in the cardiovascular division at the Mayo graduate school of Medicine. Prof Lerman serves as an associate chair and the director for research for the cardiovascular division and the director of the Mayo cardiovascular research center. Prof Lerman graduated from the Technion school of Medicine in Haifa Israel and completed his training in internal medicine, cardiovascular diseases and invasive cardiology at the Mayo

Clinic. Prof Leman interest is, coronary physiology and imaging and innovation in cardiovascular disease as well as regenerative medicine.
Prof Lerman published more than 480 manuscripts, book chapters and reviews; the NIH, AHA, and several foundations support his research.

Dr Sukhjinder Nijjer

Juliet Nilsson is the Creative Director of Simple Education, the online cardiology educational platform aggregating content from key courses, global intuitions and leaders in the field of interventional cardiology. She received a Master’s in Art History with Honours from Edinburgh University before joining the Creative Development team at Lightyears, Stockholm in 1998. Juliet continued in creative development in Copenhagen for the trail blazing e-commerce bureau AHEAD, and then as International Creative Director for Caput Community Software Solutions. Following a role as Senior Consultant at Halcyon Gallery in London and Copenhagen, Juliet founded Vind & Våg Publishing House in 2013, a creative development agency. Juliet has published several books under her own imprint and is currently the founder & advisor to the Nordic Art Agency.

Dr Ricardo Petraco

Dr Sukhjinder Nijjer is a Consultant Cardiologist with a specialist interest in Coronary Intervention and the treatment of coronary artery disease. He works at both Chelsea & Westminster NHS Foundation Trust and Imperial College Healthcare NHS Trust. Dr Nijjer is also an Honorary Clinical Senior Lecturer at Imperial College.

He has clinical research interests in coronary physiology and the treatment of acute coronary syndromes. He has a PhD awarded by Imperial College London in coronary blood flow and the use of stenting to treat complex stenoses. Clinically, he is specialises in interventional cardiology and he is skilled in coronary intervention and the application of coronary physiology and intravascular imaging. He has expertise in anti-platelets, optical coherence tomography and CT coronary angiography. He has specific research interests in coronary artery physiology and clinical trial design, and is working at the forefront of innovation in physiological assessment for coronary disease. He has presented his PhD research at the leading cardiology conferences around the world, including the European Society of Cardiology (ESC), Transcatheter Cardiovascular Therapeutics (TCT) and EuroPCR. He has won many awards and has over 70 high impact publications.

Dr Fausto Rigo

Dr Ricardo Petraco  is a NIHR Lecturer in Cardiology at Imperial College London, with a research interest in coronary physiology and interventional cardiology. He is also a Cardiology Specialist Registrar and Interventional Fellow at the Imperial College NHS Trust. After graduating in Brazil, he undertook his cardiology training in leading UK centres, including the Royal Brompton Hospital, St Mary’s Hospital and, currently, Hammersmith Hospital. He has been working with the coronary physiology group at Imperial since 2010 on the development of the novel instantaneous wave-Free Ratio (iFR). Dr Petraco’s work with iFR has led to the proposition of the Hybrid iFR-FFR approach and has established iFR’s close relationship with coronary flow reserve (CFR). Throughout his career, he has secured many research grants - CNPq grant for scientific initiation in Brazil (twice, 2000 and 2001); Imperial College Charity grant (2010); British Heart Foundation CRTF grant (2011) and Academy of Medical Sciences lecturer grant (2016) – and has published extensively in the field of coronary physiology. His interests in computer programming has led to the development of a software for automated analysis of coronary haemodynamics signals which is been used by many leading centres in the world. He has also proposed an algorithm for iFR calculation without the need for an ECG signal. His current research interests are on the development of methodologies to assess stenosis severity in situations of haemodynamic instability and on the understanding of how medical therapies modulate coronary resistance and flow. 

Dr Ricardo Petraco

Prof Patrick W. Serruys with respected h-index – 157 is a professor of Interventional Cardiology at the Interuniversity Cardiological Institute of the Netherlands (1988-1998) and Erasmus MC. Since 1980 he was a Director of the Clinical Research Program of the Catheterization Laboratory, Thorax Center at Erasmus University, and till April 1, 2014 (retirement date) the Head of the Interventional Department, Thorax Center, Erasmus MC (University Medical Center Rotterdam),

Rotterdam, The Netherlands. Since April 2013, he holds the position of Professor of Cardiology in the Cardiovascular Science Division of the National Heart and Lung Institute (NHLI) at the Faculty of Medicine, within the Imperial College of Science, Technology and Medicine, London.

He is a Fellow of the American College of Cardiology and a Fellow of the European Society of Cardiology and scientific council of the International College of Angiology.

In 1996, he received the TCT Career Achievement Award and in 1997 he was awarded the Wenkebach Prize of the Dutch Heart Foundation. In 2000, he was awarded the Gruentzig Award of the European Society of Cardiology. In 2001, he held the Paul Dudley White Lecture at the American Heart Association in the USA. In 2004, he received the Andreas Gruentzig Award of the Swiss Society of Cardiology. In 2005, he held the 4th International Lecture at the AHA and Mikamo Lecture at the Japanese heart Association. In 2006, he received the highest award of the Clinical Council of the American Heart Association: The James Herrick Award. In 2007, he received the Arrigo Recordati International Prize (Italy) and the ICI Achievement Award (bestowed by the President of Israel – Shimon Perez). In 2008, he received the Einthoven Penning (Leiden). In 2009, he became Doctor Honoris Causa from the University of Athens. In 2011, he received the Lifetime Achievement Award, bestowed by the American College of Cardiology, in recognition of many years of service and invaluable contributions to the ACC. At the end of 2011, Prof Serruys received the Ray C. Fish Award, bestowed by the Texas Heart Institute, for outstanding achievement and contribution to cardiovascular medicine. In 2012, he received a Golden Medal of the European Society of Cardiology.

In 2013, he became Doctor Honoris Causa from the Complutense University of Madrid. In 2016, he will become Doctor Honoris Causa of the Melbourne University, Australia.

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Moment Components

Welcome and introductions to Advances in Coronary Physiology Course - Dr Justin Davies
Hot topics in coronary physiology: DEFINE-FLAIR iFR; SwedeHeart; Syntax II - Prof Javier Escaned
Understanding mechanisms of regulation of resting and hyperaemic blood flow - Dr Justin Davies
Pressure derived indices of stenosis severity - Prof Javier Escaned
Getting the most out of our Advances in Coronary Physiology Courses: online-resources, and certification - Juliet Nilsson
Flow based indices of stenosis severity - Prof Amir Lerman
DEFINE-FLAIR and iFR SwedeHeart study design and results - Dr Allen Jeremias
Combined, patient-level pooled analysis of DEFINE-FLAIR and iFR SwedeHeart and safety of deferral in stable coronary disease and ACS. Does flow underlie the results? - Prof Javier Escaned
Health Economic assessment using iFR and FFR to guide revascularization decision-making. - Dr Justin Davies
How to perform iFR and FFR, and best- practice measurement tips and tricks - Dr Ricardo Petraco
Should we be using a dichotomous cut-point? Understanding mismatch between iFR and FFR from DEFINE- FLAIR and iFR SwedeHeart using flow. - Dr Christopher Cook
DEFINE-FLAIR and iFR SwedeHeart: Implication for guidelines and evaluation of coronary ischaemia - Dr Allen Jeremias
Safety of deferral in LAD, and non-LAD vessels using iFR and FFR guide approach. - Dr Justin Davies
Can PdPa or contrast be used as a substitute for iFR/FFR? - Dr Christopher Cook
Lessons learned from the 2-year results of SYNTAX II - Prof Patrick Serruys
Live case transmission from Clinico San Carlos, Madrid, Spain - Prof Javier Escaned
Should we be treating a number? Moving from vessel level ischaemia to stenosis level assessment. - Dr Justin Davies
Are we missing stenoses when we don’t perform a pressure wire pullback? - Dr Christopher Cook
Understanding SyncVision Co-registration and why it’s important to distinguish between focal and diffuse coronary disease - Dr Sukhjinder Nijjer
Using iFR Co-registration to plan revascularization decision-making: Cases examples - Dr Ricardo Petraco
How to interpret an FFR >0.80 - Prof Amir Lerman
Post PRAMI, Culprit, and Compare Acute, what role does physiology have in coronary revascularization? What other studies are needed? - Dr Sukhjinder Nijjer
Should we need stenting at all? Lessons from ORBITA - Dr Rasha Al-Lamee
Tailor-made decision-making for surgical or percutaneous revascularization based on non-invasive imaging and comorbidities: The SYNTAX III trial - Prof Patrick Serruys
Is it still too early to use CT-FFR and angio-FFR in the catheter laboratory in 2018? - Dr Christopher Cook
Physiological assessment in coronary stenosis pre TAVI - Dr Yousif Ahmad

Target Audience

This essential guide is an educational activity intended for an international audience, specifically interventional cardiologists and cardiologists. However, other healthcare professionals involved in the care of coronary artery disease (CAD) patients will also find this topical. 

This 2 day course general admission pass which covers  registration, meals, and refreshments.  After course free access to online course resources including powerpoint images, course videos, and links to other Simple Education resources.

Learning Objectives

Advances in Coronary Physiology course provides all you need to know to understand the basics of coronary physiology and what you need to do to implement coronary physiology into the cardiac catheter laboratory.

  • Understanding the background of coronary physiology

  • Understanding of coronary blood flow regulation in unobstructed and obstructed coronary arteries

  • Learn what you need to know to implement iFR and FFR in your laboratory 

  • Learn about the guidelines for appropriate use and reimbursement

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