Intracoronary Guidance in Complex PCI in Madrid, eCourse, 5 - 6th October 2020

Prof Javier Escaned is Head of Interventional Cardiology Section at Hospital Clinico San Carlos (Madrid, Spain). He trained as a cardiologist the United Kingdom before moving to the Thoraxcenter / Rotterdam (The Netherlands), where he obtained his PhD degree in 1994. A skilled interventionalist with over 30 years of experience, he regularly serves as live case operator and educationalist in global events like EuroPCR, TCT or the ESC Congress. He is author of over 400 PubMed indexed scientific articles (h-index 67) on topics that include complex PCI in multivessel disease (principal investigator of SYNTAX II study), left main and chronic total occlusions, and secondary revascularization. His track record in coronary physiology includes being investigator on pivotal FFR trials like DEFER (1998), collaborator with Justin Davies in the validation and clinical implementation of iFR (since 2010), and developer of new methods for the assessment of microvascular and non-obstructive coronary disease. Recent / ongoing trials as Co-PI include ADVISE, ADVISE II, DEFINE FLAIR and ABSORB II PHYSIOLOGY, being investigator also in ILUMIEN I and IV, COMBINE and other studies on coronary imaging. He is currently Deputy Editor for Interventional Cardiology of the European Heart Journal, as well as editor of two large textbooks: “Coronary Stenosis.
Imaging, Structure and Physiology”, (co-editor Patrick Serruys) and “Physiological Assessment of Coronary Stenoses and the Microcirculation) (co-editor Justin Davies). Current or recent board positions in scientific societies include EuroPCR, EAPCI, EuroCTO and the ESC Working Group of Coronary Pathophysiology and Microcirculation. Some of his additional interests are philosophy, education and music.

Dr Justin Davies is a consultant 
interventional cardiologist at Hammersmith Hospital, Imperial College NHS Trust, London. After training at Imperial
College, he won a prestigious BHF research fellowship to study arterial haemodynamics. Since then he has continued to
work on the development of mathematical algorithms to aid 
understanding of large artery physiology and to develop new
tools to assess arterial disease. The holder of several patents,
he has published widely in the field of hypertension, coronary and large artery physiology and is the winner of many national and international awards. He has several international collaborations, and is the developer of iFR and the co-principal investigator of the ADVISE studies, the DEFINE-FLAIR, ORBITA and DEFINE-PCI studies. Justin also has an interest in renal denervation, and has lead the first-in-man studies to evaluate the safety of this technique to patients with chronic systolic heart failure (REACH studies). 

Prof Jose M de la Torre is an interventional cardiologist, Head of Hemodynamics and Interventional department of the Marques de Valdecilla University of Santander, Spain. He is member of the scientific committee of the Spanish Society of Cardiology and is fellow of the European Society of Cardiology. Former associate director of the Trans Catheter Therapeutics Meeting in US. Faculty of ESC, PCR, ACC and TCT meetings. Coordinator of the ESTROFA, XIMA and LITRO study groups. Prof De La Torre is a member of the editorial committee of the Revista Español de Cardiologia,, Consultant editor of JACC Cardiovascular interventions, Section editor in Eurointervention and Editor in chief of REC: Interventional Cardiology. Research coordinator in EPIC foundation. In 2016-2017 he was a visiting scientist at Harvard-MIT biomedical engineering center. His research interests include intravascular imaging, coronary artery disease and drug eluting stents.

Prof Carlo Di Mario is Professor of Cardiology at the University of Florence and Director of the Structural 
Interventional Cardiology Division of the University Hospital Careggi, Florence, Italy. Previous posts included 15 years as 
Professor of Clinical Cardiology at Imperial College of Sciences,
 Medicine & Technology, London and Consultant Cardiologist at 
the Royal Brompton Hospital. He also practiced at the San 
Raffaele University Hospital, Milan, Italy. He trained in Cardiology at the 
University of Padova, Italy, but he soon moved for interventional training at the Thoraxcentre of Rotterdam, the Netherlands, where he also completed a PhD in Intracoronary Ultrasound Imaging and Doppler. Despite his teaching, research and administrative commitments, he maintains an active clinical involvement performing more than 100 PCI per year with special interest in the treatment of calcified lesions, chronic total occlusions, bifurcations, and diffuse disease. He is a regular TAVI operator and certified implanter for the Medtronic Evolut R and Edwards Sapien 3 transcatheter aortic valves. He participated in more than 260 MitraClip implantations in London and Florence and has recently started direct annuloplasty with the CardioBand. Professor Di Mario pioneered the use of intracoronary Doppler, pressure measurement, intravascular ultrasound, optical coherence tomography, and near infrared spectroscopy. He was PI of the OPTICUS trial, failing to demonstrate superiority of IVUS guided stenting, and of the Lipid Rich Plaque study, due to report at TCT 2018. He was Principal Investigator of the DESTINI trial, using Doppler CRF to identify lesions in need of stenting, and of the CARESS in AMI trial, a large multicentre trial showing that patients who receive fibrinolytic therapy for ST-elevation myocardial infarction benefit from early angioplasty. This trial and a subsequent meta-analysis have led to a change in the European Society of Cardiology and AHA/ACC Guidelines for treatment of STEMI patients. He cooperated with Dr Davies to the validation of iFR to assess lesion severity and discriminate the contribution of individual lesions, and with Dr Lyon in the intracoronary delivery of SERCA-2 genes via adenoviral vectors in the CUPID2 trial. He was the main recruiter of the DISRUPT-I-CAD study and is PI of the DISRUPT-II trial, both pioneering the use of coronary lithotripsy for calcified coronary lesions.

Dr Nieves Gonzalo is Consultant Interventional Cardiologist at the Interventional Cardiology Department at Clinico San Carlos University Hospital in Madrid. She obtained her Specialist Certification in Cardiology after training at Clinico San Carlos University Hospital in Madrid. Subsequently, she underwent a research fellowship at Thoraxcenter, Erasmus University Rotterdam (The Netherlands) under the supervision of Professor Patrick Serruys, focused mainly in intracoronary imaging and bioabsorbable stents. In 2010 she obtained her PhD with the thesis “Optical coherence tomography for the assessment of coronary atherosclerosis and vessel response after stent implantation”. Her track record includes over 170 articles indexed in PubMed, as well as book chapters in Interventional Cardiology textbooks. Recent research projects as principal investigator includes a study about the assessment of neoatherosclerosis and its clinical impact in patients with restenosis (RIBS IV and V OCT substudy) and research regarding vessel injury and healing evaluation with different stent platforms evaluated with OCT (VISTA study). Dr Gonzalo is a dedicated educationalist with involvement in many areas of complex PCI, serving currently as Deputy Editor for Eurointervention and Committee Member of EuroPCR.

Dr Allen Jeremias, MD, MSc, is the Director of Interventional Cardiology Research and Associate Director of the Cardiac Catheterization Laboratory at St. Francis Hospital, Roslyn, NY. He is also a member of the Cardiovascular Research Foundation, New York, NY where he currently serves as the Director of the Physiology Core Laboratory. He completed his Medical training at The Cleveland Clinic Foundation, Stanford University School of Medicine, as well as Beth Israel Deaconess Medical Centre, Harvard Medical School. Dr. Jeremias has numerous publications in the area of coronary physiology and intravascular imaging.

Dr Hernán Mejía-Rentería is Interventional Cardiologist at Hospital Clinico San Carlos (Madrid, Spain). He graduated from the Medical School of Universidad del Valle (Colombia) and underwent specialty training in Cardiology from 2010 to 2015 at Hospital Clinico San Carlos, Madrid, Spain. Subsequently, he completed his subspecialty training as Interventional Fellow in 2017 at the same institution. He has published numerous indexed scientific articles on coronary physiology, functional angiography, intracoronary imaging techniques and Takotsubo Syndrome, and is author of chapters in different academic textbooks. He participates actively as a reviewer of studies in the peer-review modality in different indexed scientific journals. His main research areas at present include coronary artery disease, functional angiography, intracoronary physiological assessment of ischemic heart disease and microcirculatory dysfunction. He is currently developing his doctoral thesis at the Complutense University of Madrid, focused on physiological assessment of coronary heart disease in different clinical settings.

Prof Ajay J. Kirtane, MD, SM, is Associate Professor of Medicine at Columbia University Medical Center (CUMC) and Director of the Cardiac Catheterization Laboratories at New York Presbyterian (NYP) Hospital / CUMC. Dr. Kirtane is a graduate of Princeton University and Columbia University College of Physicians and Surgeons, and completed his residency/chief residency in Internal Medicine at the University of California, San Francisco. He completed fellowships in Cardiovascular Disease and Coronary and Peripheral Vascular Intervention at Beth Israel Deaconess Medical Center / Harvard Medical School and has a Masters of Science in Clinical Epidemiology from the Harvard School of Public Health.