Conclusions and Future Directions

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Summary

Conclusions

While catheter ablation is an effective treatment option for VT suppression in patients with SHD, long-term VT suppression rates vary based on the underlying aetiology. Although prior studies have not demonstrated long-term mortality benefit, ablation is effective in reducing long-term VT recurrences, abolishing VT storm and preventing ICD shocks. The overall outcomes associated with catheter ablation are worse in patients with NICM compared with those with ischaemic substrates, which is likely the result of more complex substrates in NICM patients with a higher prevalence of intramural and/or epicardial substrates. In survivors of VT who do not yet have ICDs in place, an early ablation strategy in addition to ICD may reduce the incidence of future ICD therapies. Ongoing studies are further evaluating whether earlier catheter ablation of VT is associated with improved outcomes.

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