End-stage heart failure represents a substantial worldwide problem for the healthcare system. Despite significant improvements (medical heart failure treatment, implantable cardioverters, cardiac resyschronisation devices), long-term survival and quality of life of these patients remains poor. Heart transplantation has been an effective therapy for terminal heart failure, but it remains limited by an increasing shortage of available donor organs along with strict criteria defining acceptable recipients. For the last 50 years, mechanical alternatives to support the circulation have been investigated; however, during the early years device development has been marked in general by slow progress. However, in the past two decades, the technology has evolved dramatically. The purpose of this review is to give a short summary on the evolution of ventricular assist device (VAD) therapy and to give perspectives for future treatment of heart failure.
Dominik Wiedemann - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
Thomas Haberl - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
Julia Riebandt - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
Paul Simon - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
Günther Laufer - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
Daniel Zimpfer - Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
