Summary and Concluding Remarks
These presentations of two very different cases – one with a high bleeding risk and the other with highly stenotic lesions in different places. These illustrate the value of case studies. Clinical trials do not discuss specific cases, but in everyday practice we need to apply clinical trial data on a one-to-one basis. No single patient fits a standard profile, and numerous factors need to be considered before undergoing PCI. These include the patient’s medical history, prognosis and clinical presentation, the available instruments, devices and imaging modalities and the experience of the cardiologist (see Figure 4). Furthermore, it can be seen that there is no consensus of opinion between experts.
The Cre8 DES could be a useful addition to the range of DES employed in complex PCI cases. Its polymer-free platform with abluminal reservoirs allow targeted and controlled drug elution. The Amphilimus formulation enhances drug bioavailability and tissue permeability for optimal safety and efficacy. Furthermore, initial clinical data have demonstrated good safety and efficacy. However, data from larger prospective trials are required to ascertain the true effectiveness of the Cre8 DES in complex lesions.