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CMR, using different sequences, can be of great value for the early and accurate assessment of cardiac involvement due to systemic diseases. CMR is a powerful technique that offers reliable and operator-independent assessment of cardiac anatomy, function, stress perfusion-fibrosis, myocardial-vessel inflammation, aortic distensibility, and iron and fat deposition; additionally it can identify disease acuity. These applications make the technique an excellent tool for heart-vessels assessment, risk stratification and treatment evaluation of patients with systemic diseases.

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