Transcatheter aortic valve implantation (TAVI) has undergone tremendous technological advancements since the first successful implantation in 2002 for symptomatic severe aortic valve stenosis (AS).1 It is currently considered as the standard of care for severe AS patients who have high surgical risk or may be deemed unsuitable for surgery.2 Broadly, there are two main categories of transcatheter aortic valve prostheses: balloon-expandable (BE) and self-expandable (SE). Limited data exists as to whether there are significant differences in clinical outcomes with these two different prosthesis types. As newer prosthesis generations become available and the indications for TAVI expand to include additional patients and indications, such as those with intermediate surgical risk,3 valve-in-valve procedures4 and bicuspid AS,5 it has become relevant to have comparative efficacy and safety data of contemporary BE and SE prostheses. This evidence-based focused review aims to provide an overview of the valve characteristics and the factors influencing prosthesis selection, imbibing data from the literature on the clinical outcomes of BE and SE TAVI prostheses.