Conclusion
IVUS-based imaging modalities allow us to improve our understanding of atherosclerotic disease and vulnerable plaque. Radiofrequency IVUS analysis enables identification of patients at high risk for future cardiovascular events and adverse outcomes following PCI. It can also be used to evaluate the effect of pharmacological treatment on coronary plaque morphology. Although IVUS radiofrequency analysis is a promising tool for identification of vulnerable plaque, the limitations are unproven clinical benefit and overall cost effectiveness. More research and randomised trials are needed to answer whether or not routine IVUS radiofrequency imaging is clinically relevant.